CD40L / CD154抗体 [MR1] (生物素 biotin)
目录号 GTX01485-02
目录号 GTX01485-02
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宿主Armenian Hamster
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克隆Monoclonal
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克隆编号MR1
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同种型IgG
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实验应用FCM
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种属反应Mouse
摘要
The MR1 antibody is specific for mouse CD154, a 39 kD glycoprotein that is primarily expressed on activated T cells. CD154 (CD40 ligand, gp39) binds to CD40 expressed on antigen presenting cells and mediates important costimulatory functions between these cells. Signals generated via cognate interactions between CD154-CD40 on activated T and B cells are required for T-dependent B cell responses. The MR1 antibody is reported to block interaction of CD154 with CD40.