G蛋白偶联受体 (GPCRs) | GeneTex中文官方网站

GeneTex is committed to establishing the most extensive product line of recombinant monoclonal antibodies for human GPCRs. These antibodies will be thoroughly characterized through enhanced “Five Pillar” validation strategies that feature knockdown/knockout lysates, comparable antibodies, cell fractionation, detection of endogenous GPCR expression, and overexpression. In addition, specialized testing using human GPCR arrays will be utilized when feasible. The goal is to generate the most diverse, expansive, and meticulously verified antibody reagents for GPCR biology research.

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Explore Our GPCR Antibodies

Class A

Subclass	Target
5-hydroxytryptamine	5-hydroxytryptamine Receptor 4 (HTR4)
5-hydroxytryptamine	5-hydroxytryptamine Receptor 7 (HTR7)
5-hydroxytryptamine	5-hydroxytryptamine Receptor 1E (5-HT1E)
Acetylcholine	Cholinergic Receptor Muscarinic 1 (mAChR M1)
Adenosine	Adenosine A1 Receptor (ADORA1)
Adenosine	Adenosine A2a Receptor (ADORA2A)
Adenosine	Adenosine A2b Receptor (ADORA2B)
Adrenoceptors	Alpha 1a Adrenergic Receptor (ADRA1A)
Adrenoceptors	Alpha 1b Adrenergic Receptor (ADRA1B)
Adrenoceptors	Alpha 1d Adrenergic Receptor (ADRA1D)
Adrenoceptors	Alpha 2a Adrenergic Receptor (ADRA2A)
Adrenoceptors	Alpha 2b Adrenergic Receptor (ADRA2B)
Adrenoceptors	Beta 1 Adrenergic Receptor (ADRB1)
Adrenoceptors	Beta 2 Adrenergic Receptor (ADRB2)
Adrenoceptors	Beta 3 Adrenergic Receptor (ADRB3)
Angiotensin	Angiotensin II Receptor Type 1 (AGTR1)
Apelin	Apelin Receptor (APLNR)
Cannabinoid	Cannabinoid Receptor 2 (CNR2)
Chemokine	C-C Motif Chemokine Receptor 1 (CCR1)
Chemokine	C-C Motif Chemokine Receptor 2 (CCR2)
Chemokine	C-C Motif Chemokine Receptor 4 (CCR4)
Chemokine	C-C Motif Chemokine Receptor 5 (CCR5)
Chemokine	C-C Motif Chemokine Receptor 7 (CCR7)
Chemokine	C-C Motif Chemokine Receptor 9 (CCR9)
Chemokine	C-C Motif Chemokine Receptor 10 (CCR10)
Chemokine	Atypical Chemokine Receptor 4 (CCR11)
Chemokine	C-X-C Motif Chemokine Receptor 1 (CXCR1)
Chemokine	C-X-C Motif Chemokine Receptor 2 (CXCR2)
Chemokine	C-X-C Motif Chemokine Receptor 3 (CXCR3)
Chemokine	C-X-C Motif Chemokine Receptor 4 (CXCR4)
Chemokine	C-X-C Motif Chemokine Receptor 5 (CXCR5)
Chemokine	C-X-C Motif Chemokine Receptor 6 (CXCR6)
Chemokine	Atypical Chemokine Receptor 3 (CXCR7)
Cholecystokinin	Cholecystokinin B Receptor (CCKBR)
Chemokine	C-X3-C Motif Chemokine Receptor 1 (CX3CR1)
Class A Orphans	G Protein-Coupled Receptor 15 (GPR15)
Class A Orphans	G Protein-Coupled Receptor 21 (GPR21)
Class A Orphans	G Protein-Coupled Receptor 23 (GPR23)
Class A Orphans	G Protein-Coupled Receptor 31 (GPR31)
Class A Orphans	G Protein-Coupled Receptor 45 (GPR45)
Class A Orphans	G Protein-Coupled Receptor 50 (GPR50)
Class A Orphans	G Protein-Coupled Receptor 88 (GPR88)
Class A Orphans	G Protein-Coupled Receptor 126 (GPR126)
Class A Orphans	G Protein-Coupled Receptor 148 (GPR148)
Class A Orphans	Leucine Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5)
Class A Orphans	Leucine Rich Repeat Containing G Protein-Coupled Receptor 6 (LGR6)
Class A Orphans	MAS Related GPR Family Member F (MRGPRF)
Class A Orphans	MAS related GPR family member X1 (MRGX1)
Complement	Complement C3A Receptor 1 (C3AR1)
Complement	Complement Component 5a Receptor 2 (C5L2)
Dopamine	Dopamine Receptor D1 (DRD1)
Dopamine	Dopamine Receptor D2 (DRD2)
Dopamine	Dopamine Receptor D4 (DRD4)
Dopamine	Dopamine Receptor D5 (DRD5)
Endothelin	Endothelin Receptor Type B (Ednrb)
Estrogen	G protein-coupled estrogen receptor 1 (GPR30)
Formylpeptide	Formyl Peptide Receptor 1 (FPR1)
Formylpeptide	Formyl Peptide Receptor 2 (FPRL1)
Free fatty acid	Free Fatty Acid Receptor 1 (GPR40)
Free fatty acid	Free Fatty Acid Receptor 2 (GPR43)
Free fatty acid	Free Fatty Acid Receptor 4 (GPR120)
Ghrelin	Growth Hormone Secretagogue Receptor (GHS-R1)
Hormones (TSH, FSH, and GnRH)	Follicle Stimulating Hormone Receptor (FSHR)
Hormones (TSH, FSH, and GnRH)	Thyroid Stimulating Hormone Receptor (TSHR)
Hormones (TSH, FSH, and GnRH)	Gonadotropin Releasing Hormone Receptor (GnRHR)
Histamine	Histamine Receptor H1 (HRH1)
Hydroxycarboxylic acid	Hydroxycarboxylic Acid Receptor 1 (GPR81)
Kisspeptin	KISS1 Receptor (GPR54)
Lysophospholipid	Lysophosphatidic Acid Receptor 2 (EDG-4/LPAR2)
Lysophospholipid	PAF Receptor (PTAFR)
Lysophospholipid	Sphingosine-1-phosphate Receptor 2 (S1PR2)
Lysophospholipid	Sphingosine-1-phosphate Receptor 5 (S1PR5)
Melanocortin	Melanocortin 1 Receptor (MC1R)
Melanocortin	Melanocortin 4 Receptor (MC4R)
Melanocortin	Melanocortin 5 Receptor (MC5R)
Neuromedin U	Neuromedin U Receptor 2 (NMUR2)
Opioid	Opioid Receptor Delta 1 (OPRD1)
Opioid	Opioid Receptor Mu 1 (OPRM1)
Opioid	Opsin Blue (OPN1SW)
Opsins	Opsin Red / Green (OPN1MW2)
Opsins	Retinal G Protein Coupled Receptor (RGR)
Opsins	Rhodopsin (RHO)
Prostanoid	Prostaglandin E Receptor 3 (PTGER3)
Proteinase-activated receptor	F2R Like Trypsin Receptor 1 (PAR2)
Proteinase-activated receptor	Coagulation Factor II Thrombin Receptor Like 2 (PAR3)
Relaxin family	Relaxin Family Peptide Receptor 1 (LGR7)
P2Y	Purinergic Receptor P2Y1 (P2Y1)
P2Y	Purinergic Receptor P2Y2 (P2Y2)
P2Y	Purinergic Receptor P2Y11 (P2Y11)
P2Y	Purinergic Receptor P2Y12 (P2Y12)
Somatostatin	Somatostatin Receptor 2 (SSTR2)
Somatostatin	Somatostatin Receptor 3 (SSTR3)
Somatostatin	Somatostatin Receptor 4 (SSTR4)
Somatostatin	Somatostatin Receptor 5 (SSTR5)
Tachykinin	Neurokinin 1 Receptor (NK1R)

Class B1

Subclass	Target
Calcitonin	Calcitonin Receptor Like Receptor (CRLR)
Glucagon family	Glucagon Like Peptide 1 Receptor (GLP1R)
Parathyroid	Parathyroid Hormone 1 Receptor (PTH1R)
VIP and PACAP	Vasoactive Intestinal Peptide Receptor 2 (VPAC2)

Class B2

Learn more about adhesion GPCRs

Subclass	Target
Adhesion	Adhesion G Protein-Coupled Receptor B1 (BAI1)
Adhesion	Adhesion G Protein-Coupled Receptor B2 (BAI2)
Adhesion	Adhesion G Protein-Coupled Receptor B3 (BAI3)
Adhesion	Adhesion G protein-Coupled Receptor E1 (F4/80)
Adhesion	Adhesion G Protein-Coupled Receptor E2 (EMR2)
Adhesion	Adhesion G Protein-Coupled Receptor E5 (CD97)
Adhesion	Cadherin EGF LAG Seven-Pass G-type Receptor 1 (CELSR1)
Adhesion	Cadherin EGF LAG Seven-Pass G-type Receptor 2 (CELSR2)
Adhesion	Adhesion G Protein-Coupled Receptor G3 (GPR97)
Adhesion	Adhesion G Protein-Coupled Receptor G5 (GPR114)
Adhesion	Adhesion G Protein-Coupled Receptor F5 (GPR116)
Adhesion	Adhesion G protein-Coupled Receptor A1 (GPR123)
Adhesion	Adhesion G protein-Coupled Receptor G6 (GPR126)
Adhesion	Adhesion G protein-Coupled Receptor D1 (GPR133)
Adhesion	Adhesion G protein-Coupled Receptor L1 (Latrophilin 1)
Adhesion	Adhesion G protein-Coupled Receptor L2 (Latrophilin 2)
Adhesion	Cadherin EGF LAG Seven-Pass G-Type Receptor 2 (CELSR2)

Class C

Subclass	Target
Calcium-sensing	Calcium Sensing Receptor (CASR)
Class C Orphans	G Protein-Coupled Receptor Class C Group 5 Member A (GPRC5A)
Class C Orphans	G protein-Coupled Receptor Class C Group 5 Member C (GPRC5C)
Class C Orphans	G protein-Coupled Receptor Class C Group 5 Member D (GPRC5D)
GABA	Gamma-aminobutyric Acid Type B Receptor Subunit 1 (GABBR1)
GABA	Gamma-aminobutyric Acid Type B Receptor Subunit 2 (GABBR2)
Metabotropic glutamate	Glutamate Metabotropic Receptor 1 (mGluR1)
Metabotropic glutamate	Glutamate Metabotropic Receptor 4 (mGluR4)
Metabotropic glutamate	Glutamate Metabotropic Receptor 5 (mGluR5)
Metabotropic glutamate	Glutamate Metabotropic Receptor 6 (mGluR6)

Class F

Subclass	Target
Frizzled	Frizzled 1 (FZD1)
Frizzled	Frizzled 4 (FZD4)
Frizzled	Frizzled 8 (FZD8)
Frizzled	Frizzled 9 (FZD9)
Frizzled	Smoothened Homolog (SMO)

Taste 2

Subclass	Target
Taste 2	Taste 1 Receptor Member 2 (TAS1R2)
Taste 2	Taste 2 Receptor Member 38 (TAS2R38)

Learn more about GPCRs

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