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Summary Recognizes the low molecular weight (Mr 180kDa) isoform of the leucocyte common antigen (LCA) which is part of a family of protein tryosine phosphatases. The CD45RO antigen is present on most thymocytes, about 40% of resting peripheral blood T-lymphocytes and the majority of T-cells in skin reactive infiltrates and T-cell malignancies. CD45RO is also found on a subset of B-cells and some B-cell lymphomas. NK cells do not express the CD45RO antigen. It is also present on monocytes, macrophages and granulocytes.

Summary Rat CD45RC