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BRCA1 antibody [17F8] - ChIP grade Cat No. GTX70111

27 引用文献

KO/KD Orthogonal Carrier-Free

Summary This antibody does not recognize the delta exon 11 splice variant of BRCA1. In a high proportion of breast and ovarian cancer cell lines, BRCA1 aberrantly mislocates to the cytoplasm.

AKR1C1 antibody Cat No. GTX105620

2 21 引用文献

KO/KD Orthogonal Overexpression

Summary Based on sequence homology, this antibody may cross react with AKR1C2, AKR1C3, or AKR1C4 protein.
KO/KD validation is based on published data (PMID: 32104503).

EGFR antibody [GT133] Cat No. GTX628887

7 引用文献

KO/KD Comparison Orthogonal Overexpression IP/MS Carrier-Free

Summary This antibody was raised against human EGFR Intracellular domain.This antibody does not cross-react with Her2/Erbb2 protein.
IP/MS validation is based on published data (PMID: 30377423).

LOXL2 antibody Cat No. GTX105085

22 引用文献

KO/KD Orthogonal Overexpression

Summary Mouse reactivity has been validated by IHC-P only, not yet been tested by other applications.
KO/KD validation is based on published data (PMID: 32211324).

Summary Recognizes an internal, highly conserved amino acid sequence (VQEALD and VQAALD) found in both protein isoforms, P-glycoprotein and MDR3 P-glycoprotein. Specific reactivity to human, mouse, rat, dog and primate. Detects bands of ~170kDa (MDR1 P-glycoprotein) and of ~140kDa (MDR3 P-glycoprotein) by Western blot.